<![CDATA[Down syndrome (DS) is a chromosomal disorder linked to intellectual impairment and developmental delays in babies. The primary prenatal indicator for detecting DS during the initial stages of gestation is the thickness of nuchal translucency (NT). This paper introduces a GoogLeNet model based on convolutional neural networks (CNN) for the semantic segmentation of the NT region from ultrasound fetal images, facilitating rapid and cost-effective diagnosis in the early stages of the gestational period. A transfer learning methodology with AlexNet is employed to train the NT regions for the detection of DS. The Inception module of GoogLeNet enables the model to simultaneously capture characteristics at various sizes of images. The capacity to extract both intricate and broad characteristics can improve the model’s performance in precisely identifying the NT area. This will function as an exceptional tool for physicians in screening of DS, enhancing the detection rate and providing a substantial opinion for early diagnosis. The proposed deep learning approach attained an accuracy of 96.18% and Jaccard index of 0.967 for NT region segmentation utilizing GoogLeNet. A confusion matrix was used to evaluate the image classification by AlexNet model's effectiveness, and the results showed an overall accuracy of 97.84%, ROC-AUC of 98.45%, recall of 99.64%, precision of 96.04%, and F1 score of 97.80%. The proposed deep learning method produced remarkable outcomes and can be applied to the identification of DS in medical field. This method identifies individuals at increased risk for this condition and enables termination in the early stages of pregnancy.]]>
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