<![CDATA[Purpose: The cardiovascular system is a vital system responsible for the distribution of oxygen and nutrients throughout the body. The complexity of interactions between the heart and blood vessels often presents challenges in monitoring and analyzing health conditions. The research proposes the development of a Human Digital Twin (HDT) for the cardiovascular system through application of two different modelling approaches geometric modeling and physic-based modeling. Through this model physical conditions can be represented and real time data integrated to offer insights into the dynamics of the cardiovascular system. Methods: This model development is based on two major components: a geometric modeling and a physic-based modeling. The geometric model is done in 3D to show the structure of the heart in detail, while the physical-based model is tabulated with different measurable physical parameters in the cardiovascular system, such as blood pressure and flow rate. This information is integrated into the Five Dimension Digital Twin model, including physical, virtual, data, connection, and service dimensions for the accurate simulation of cardiovascular conditions. Result: Results confirm that the Five-Dimensional Digital Twin (DT) could give further development to how the dynamics of the cardiovascular system behave, possibly in real-time updates on conditions and a supply of data that is far more detailed in view of analyzing risk and further representation of specific cardiovascular disorders while providing personalized medical support. Novelty: The Five-Dimensional Human Digital Twin Model (HDTM) developed in this research introduces novel innovations in the monitoring and simulation of the cardiovascular system through the application of geometric and physic-based modeling techniques. This approach offers a higher level of detail, compared to previous models, and added value for the advancement of health technology by integrating real time data into the simulations. This model serves not only as an advanced analytical tool but also as a reference for further research on DT technology in the medical field.]]>
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