Tuberculosis is the deadliest infectious disease in Indonesia, and West Java is a province with the largest number of tuberculosis cases in Indonesia. This research was conducted to identify variables and groups of variables that could explain the number of tuberculosis cases in West Java. The data used has many explanatory variables, and these variables form groups. LASSO and group LASSO analysis can be used for variables selection and handle data that has many explanatory variables, and group LASSO analysis can be used on data with grouped variables. The results of the LASSO analysis, variables that can explain the number of tuberculosis cases in West Java are the number of people with disabilities, the number of pharmacy staff, the number of malnourished people, the number of people working and the number of cities. According to the group LASSO analysis, the variables that can explain the number of tuberculosis cases in West Java are variables in the health and environmental groups. The government can focus on these factors if they want to reduce the number of tuberculosis cases in West Java.
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