Having a child with perfect physical and psychological condition is everyone's dream. However, if the diagnosis states that the child has autism, it is not certainly easy for parents to accept. This aims of research are determining the sincerity of parents who have children with autism and what the factors which influence it. This research uses a descriptive qualitative method with a muslim couple, husband and wife, which have two autism children as subjects. The results showed that process towards sincerity between two subjects were different. When The SP subject knows the diagnosis results, he can control his emotions that what happened with them is God's provision. so that no matter what the conditions are, he must accept it. Meanwhile, SR subject took two weeks to convince herself about her children's conditions were still gifts from God and she must have to take care. The factors which influences of parents' sincerity are religious knowledges, patience, gratitude, religious understanding and resignation.
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