<![CDATA[With increasing threats in cyberspace, maintaining the integrity of electronic medical data is crucial. This study aims to develop a method that integrates encryption using Advanced Encryption Standard (AES) and compression with the Lempel-Ziv-Markov Algorithm (LZMA) to protect DICOM files containing sensitive information. This method is designed to address two main challenges: the growth of file sizes after the encryption process and the efficiency in data storage. In this study, an experimental design with random sampling was applied, testing 427 DICOM files from open libraries ranging in size from 513.06 KB to 513.39 KB to evaluate the implementation of this method in reducing file size, encryption time, and maintaining data integrity. The results show that this method is able to reduce file size by between 40-50% with an average encryption time of about 0.2-0.3 seconds per file. In addition, the data remains intact before and after the encryption process, which indicates that the integrity of the data is well maintained. Further analysis revealed that CPU usage during the encryption process reached 94.05%, while memory usage was recorded at 92.95 KB. In contrast, in the decryption process, CPU usage decreased to 78.16% with a much lower memory consumption, which was 31.07 KB. The findings have significant implications for medical information systems, allowing developers to easily implement these methods through APIs. This research is expected to be a reference for future studies that focus on data security in health information systems and provide new insights into the combination of encryption and compression in the context of medical data.]]>
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