Journal of Medicine and Health
Vol 1 No 3 (2016)

The Potential of MiRNAs as Biomarkers and Therapy Targets for Cancer

Teresa L. Wargasetia (Unknown)

Article Info

Publish Date
28 Feb 2016

Abstract

MicroRNAs (miRNAs) are involved in the signaling circuits regulation within a cell andtheir deregulation plays an important role in cancer development and progression. In thisreview, we discussed miRNA biogenesis, miRNA function and the effect of miRNA abnormalitiesin cellular pathways that led to transformation of normal cells into cancer cells, as well as theindication of miRNAs as diagnostic and prognostic biomarkers of various types of cancer, asbiomarkers to predict the response to cancer therapy and the potential for development ofmiRNAs as cancer targeted therapy.Keywords: miRNA, cancer, diagnostic biomarker, prognostic biomarker, cancer therapy

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Journal Info
Journal of Medicine and Health
Website

Abbrev

jmh

Publisher

Universitas Kristen Maranatha

Subject

Medicine & Pharmacology Public Health

Description

Journal of Medicine and Health (JMH) focuses on contributing towards science and research development that can be accessed by researchers and academic practitioners. Journal of Medicine and Health (JMH) is an open access journal, published biannually on every February and August. JMH receives ...