Cermin Dunia Kedokteran
Vol 49 No 9 (2022): Neurologi

Sindrom Guillain-Barre sebagai Gejala COVID-19 dan Potensi Efek Samping Pasca-Vaksinasi COVID-19

Joanesa Della Felista (Fakultas Kedokteran dan Ilmu Kesehatan Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia)
Budi Riyanto Wreksoatmodjo (Fakultas Kedokteran dan Ilmu Kesehatan Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia)



Article Info

Publish Date
01 Sep 2022

Abstract

COVID-19 adalah penyakit infeksi virus SARS-CoV-2. Gejala umum COVID-19 adalah pada saluran pernapasan, namun dapat ditemukan gejala neurologis antara lain sindrom Guillain-Barré (GBS). Hingga saat ini prevalensi kasus GBS pada pasien COVID-19 sekitar 0,15%. Selain itu, GBS juga dapat merupakan salah satu efek samping setelah pemberian vaksin COVID-19. Insiden GBS lebih banyak pada penerima vaksin viral vector (0,38/100.000 dosis) dibandingkan penerima vaksin mRNA (0,18/100.000 dosis). Hingga saat ini belum ada laporan kasus GBS pasca-vaksinasi berbasis protein. Hampir semua kasus GBS baik yang menerima vaksin berbasis mRNA maupun viral vector menunjukkan respons baik terhadap terapi IVIg.   COVID 19 is primarily a respiratory viral infection, but there are reports of neurological symptoms among patients; one of the accompanying neurological symptoms is Guillain-Barré Syndrome (GBS). Its prevalence among COVID 19 patients is approximately 0.15%. GBS is also reported as a side effect after COVID vaccinations. Its incidence in greater among viral vector vaccine recipients (0.38/100.000 doses) as compared to mRNA vaccine recipients (0.18/ 100.000 doses). No GBS case was reported after protein-based vaccine administration. The majority of cases responded well after IVIg therapy.

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Journal Info

Abbrev

cdk

Publisher

Subject

Health Professions

Description

Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK ...