Treatment of temporomandibular joint osteoarthritis using dental stem cell secretome: Perawatan temporomandibular joint osteoarthritis menggunakan dental stem cell secretome

Nurul Auliya
Ikbal, Muhammad
Jubhari, Eri Hendra

MDJ (Makassar Dental Journal)
Vol. 14 No. 1 (2025): Volume 14 Issue 1 April 2025

Temporomandibular joint osteoarthritis (TMJ-OA) is caused by disc dislocation, trauma, functional overload, and developmental abnormalities. One of the effectively used TMJ-OA treatments is dental stem cell secretome (DSECR); it has shown promising po-tential in cartilage regeneration. This review analyses DSECR as having the potential to halt or suppress the progression of TMJ-OA. It was concluded that treatment using DSECR promoted regeneration and repair of chemically induced TMJ-OA, indicating that DSECR has great potential to be a cell-free therapeutic approach.