The monkeypox outbreak has again become a global concern due to its widespread spread in various countries. Information related to the disease is widely shared through social media, especially Twitter which is a major source of public opinion. However, the complexity of language and the diverse viewpoints of users often pose challenges in accurately analyzing sentiment. Therefore, sentiment analysis of tweets about monkeypox is important to understand public perception and its impact on the dissemination of health information. This research contributes to identifying the most effective word embedding-based feature extraction method for sentiment analysis of health issues on social media. The purpose of this study is to compare the performance of word embedding methods namely Word2Vec, GloVe, and FastText in sentiment analysis of tweets about monkeypox using the BiLSTM model. Data totaling 1511 tweets were collected through a crawling process using the Twitter API. After the data is collected, manual labeling is done into three sentiment categories, namely positive, negative, and neutral. Furthermore, the data is processed through a preprocessing stage which includes data cleaning, case folding, tokenization, stopword removal, and stemming. The evaluation results show that FastText with BiLSTM produces the highest accuracy of 90%, followed by Word2Vec at 89%, and GloVe at 87%. FastText proved to be more effective in reducing classification errors, especially in distinguishing between negative and positive sentiments due to its ability to capture subword information and broader context. These findings suggest that the use of FastText can improve the accuracy of sentiment analysis, especially on health issues that develop on social media, so that it can support data-driven decision making by relevant parties in handling information dissemination. 
                        
                        
                        
                        
                            
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