<![CDATA[Abstract: Photoaging is a skin aging process that occurs due to sun exposure causing damage to the skin. From the results of the study, it was also found that the most visible signs of premature aging were not fine lines or wrinkles, but dull skin with a percentage of 53.30%. Snakehead fish has a protein level in 100 grams of fish meat reaching 25.2 grams. The albumin level of snakehead fish is quite high up to 6.22%, and the zinc mineral content from snakehead fish reaches 1.74 mg/100 grams, with high levels of protein and albumin snakehead fish useful as photoaging therapy. This study aims to find out whether there is a difference in effect between the use of Channa striata (snakehead fish) extract cream and 0.1% tretinoin cream as photoaging therapy. This type of study is a randomized control trial using 2 groups, namely the group with the administration of snakehead fish cream test material and the group with the 0.1% tretinoin cream test material for 30 days with a total sample of 96 people, each sample will be observed at the beginning and end of the treatment using the Glombau scale. Based on the results of the study, there was no difference in effectiveness between the use of Channa Striata (snakehead fish) extract cream and 0.1% tretinoin cream on photoaging (p=1.00). There was no comparison of effectiveness between the use of Channa Striata (snakehead fish) extract cream and 0.1% tretinoin cream on photoaging.]]>
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