The prevalence of Stevens Johnson Syndrome caused by antiretroviral in hospitalized patients at Dr. Hasan Sadikin General Hospital Bandung

Maelani, Nurmilah
Sufiawati, Irna
Darmadji, Hartati Purbo

Padjadjaran Journal of Dentistry
Vol 21, No 3 (2009): November

Stevens-Johnson Syndrome is a mucocutaneous disease caused by allergic drug eruption. Antiretroviral (ARV) therapy for HIV/AIDS patient may cause allergic drug eruption such as Stevens-Johnson Syndrome.The aim of this research was to find out the prevalence of Stevens-Johnson Syndrome caused by ARV in hospitalize patient at Dr.Hasan Sadikin General Hospital Bandung from January to December 2008.It was a descriptive research by taking the secondary data from patient’s medical record. The result of this research showed that from 20 Stevens-Johnson Syndrome patients, 12 persons of them (60%) are men.Most of the patients were between the age of 20-29 (45%).Oral manifestation of Stevens-Johnson Syndrome seen in 100% patients.Prevalence of Stevens-Johnson Syndrome caused by ARV was 28.6% which seen in 8 HIV/AIDS patients.ARV combination consists of nevirapine, lamivudine, and zidovudine was the most (50.0%) ARV which suspected causing Stevens-Johnson Syndrome.The conclusion of this research showed that the prevalence of Stevens-Johnson Syndrome caused by ARV in hospitalize patient at Dr.Hasan Sadikin General Hospital Bandung 2008 was 28.6% seen in 8 HIV/AIDS patients.