Antibacterial Potential of Parem Karo to Treat Staphyloccocus aureus Infection in Diabetic Foot Patients

Tarigan, Jenny Alfa Dilla Br
Sembiring, Novitaria Br
Bangar S., Roy Idrianto

TRANSPUBLIKA INTERNATIONAL RESEARCH IN EXACT SCIENCES (TIRES)
Vol. 4 No. 2 (2025): APRIL

One of the chronic and serious complications of diabetes mellitus is diabetic foot. Staphylococcus aureus bacteria is the most common bacteria found in this type of wound. The purpose of this study is to determine the antibacterial activity of parem Karo, which is one of the traditional medicines of the ethnic culture of the Karo tribe which is rich in spices. The results showed inhibitory activity at higher concentrations with the largest average inhibition diameter at 75% concentration against Staphyloccocus aureus bacteria (8.23 ± 0.72 mm) followed by 50% concentration with an average inhibition diameter (7.52 ± 0.2 mm) and at 25% concentration showed no inhibition zone at all. The conclusion obtained from this study is that there is antibacterial activity of Karo hot parem extract at a concentration of 75% and 50% against the growth of Staphyloccocus aureus bacteria.