Irrigation of root canal is an essential part that supports the success of root canaltreatment as it removes necrotic tissues, microorganisms and dentin chips frominfected root canal through flushing of irrigants. Despite its usefulness as anantimicrobial agent, irrigants are also toxic that can cause irritations wheninadvertently forced into the periapical tissue. The choice of irrigants needs goodknowledge of irrigants’ characteristics, undertsanding an appropriate technique ofirrigation, and type of microorganisms involved in root canal infection that supportthe effectiveness of irrigants. This paper is aimed to discuss the characteristics ofsome irrigants commonly used in root canal treatment and also to present the resultsobtained from some clinical investigations.
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