<![CDATA[Recurrent oral herpes simplex infection was the secondary or recurrent form of primary herpes simpex infection. Inhuman, herpes simplex virus was latent or dormant and could reactivate. Recurrency due to virus reactivation inducedby emotional stress, high fever, ultraviolet exposed, oral tissue or neuron tissue trauma, immunosuppresion condition,and hormonal disturbance. The aim of this paper was to report and discuss management of recurrent oral herpessimplex infection which complicated in the diagnosis due to manifestation of both herpes labialis and intraoral lesionform resembling herpes simplex infection. Patient was a 22 years- old woman, came to Installaton of Dental, dr.Soetomo Hospital with chief complaint pain were soreness caused by ulcer on the tongue accompanied by tingling nearthe upper labial mucosal. Patient was prescribed with acyclovir as causative therapy, mouthwash contain extract ofaloe vera, multivitamins and immunomodulator as supportive therapy. Patient healed 4 days after the first visit. It wasconcluded that this case was diagnosed clinically as recurrent oral herpes simplex infections. Causative therapy withacyclovir administration showed excellent response, as well as supportive therapy immunomodulator that supportedimprovement of the immune system so that the frequency of recurrence can be reduced.]]>
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