Kadar TNF-α dan IL-1β cairan sulkus gingiva setelah pemasangan mahkota akrilik

Edy Machmud (Bagian Prostodonsia Fakultas Kedokteran Gigi Universitas Hasanuddin)
Roswita Roswita (Bagian Prostodonsia Fakultas Kedokteran Gigi Universitas Hasanuddin)

Journal of Dentomaxillofacial Science
Vol. 6 No. 1 (2007): Formerly Jurnal Dentofasial ISSN 1412-8926

Cervical margin of fixed denture either jacket crown or bridge, is usually placedsubgingivally for the natural look, however this can sometimes cause gingivalinflammation. Moreover, if the restoration material is acrylic, it sometimes can irritateoral tissue. The aim of this study was to investigate the effect of acrylic, used as fixeddenture material, to gingival tissue reaction. This was an experimental study, using preand post test of 5 acrylic jacket crowns, made to patients in the ProsthodonticDepartment, Dental Hospital of Hasanuddin University. Gingival crevicular fluid (GCF)was collected before preparation, and three weeks after insertion of the jacket crowns,then pro-inflammatory cytokines; TNF-α and IL-1β were examined. The results analyzedby Wilcoxon sign rank test (p<0.05). The results showed the elevation of TNF-α and IL1βconcentration after acrylic jacket crown insertion compare with the concentrationbefore preparation. The conclusion of this study is acrylic restoration material may causegingival inflammation.