MEDICINUS
Vol. 38 No. 5 (2025): MEDICINUS

The Role of Hypocalcemia in Preeclampsia: A Review on Calcium Supplementation in Pregnancy

Dimas Kirana Mahaputra (Unknown)



Article Info

Publish Date
02 May 2025

Abstract

Preeclampsia is a hypertensive disorder that contributes to the high maternal death rate worldwide. Furthermore, preeclampsia adversely affects fetal development due to reduced placental blood flow. Numerous factors are known to affect the development and pathophysiology of preeclampsia, one of them is micronutrient deficiency. Calcium, an essential mineral, plays a crucial role in the mechanism of vascular smooth muscle contraction, which regulates vascular tone and blood pressure. Placental dysfunction, a hallmark of preeclampsia, leads to hypocalcemia, which, in turn, exacerbates the condition through compensatory mechanisms involving parathyroid hormone. Conversely, adequate calcium intake has been proven beneficial and is recommended during pregnancy. This article aims to review current guidelines on calcium supplementation and nutritional recommendations as a viable strategy to minimize the risk of preeclampsia.

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Journal Info

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journal

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Description

Tujuan penerbitan jurnal Medicinus adalah untuk meningkatkan wawasan dan menambah khasanah pengetahuan para praktisi medis dan farmasis di bidang kedokteran dan kefarmasian. Ruang lingkup dari jurnal ilmiah ini adalah publikasi artikel-artikel ilmiah yang bisa disajikan dalam bentuk penelitian ...