Jurnal Biologi Tropis
Vol. 25 No. 2 (2025): April-Juni

Case of Tinea Corporis on The Back Treated with Topical Terbinafine

Idris, Irma Suryani (Unknown)



Article Info

Publish Date
30 May 2025

Abstract

Dermatophytes, which are fungi that grow on keratin, are the cause of tinea corporis, a superficial fungal infection of the skin of the body (apart from the scalp, face, and groin). At the dermatovenereology polyclinic of a Makassar hospital, a 19-year-old teen was diagnosed with tinea corporis. The diagnosis was made based on clinical features, direct microscopic examination (10% KOH). Long, branched hyphae with some hyphae starting to separate. The patient was treated with topical terbinafine and clinical and mycological improvement. Therapy was continued with topical terbinafine for a month. Terbinafine is a fungicidal antifungal drug that works by inhibiting ergosterol biosynthesis. Patients treated topically were given topical terbinafine applied twice a day. Without ergosterol, the fungal cell membrane is damaged and cell function is disrupted, causing fungal death. Terbinafine is the first line for tinea corporis and cruris, because it is more effective and has a shorter treatment duration than ketoconazole or other azoles. The results of this case examination after 14 days of treatment showed improvement, negative KOH results, clinical symptoms such as itching were greatly reduced and topical medication was continued. The patient was asked to come for a check-up, treatment continued until the lesions on the back disappeared.

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Journal Info

Abbrev

JBT

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

Description

Jurnal Biologi Tropis (ISSN Cetak 1411-9587 dan ISSN Online 2549-7863) diterbitkan mulai tahun 2000 dengan frekuensi 2 kali setahun oleh Program Studi Pendidikan Biologi PMIPA FKIP Universitas Mataram, berisi hasil penelitian dan ulasan Ilmiah dalam bidang Biologi ...