Positron Emission Tomography and Computed Tomography (PET/CT), a key imaging modality in nuclear medicine, Combines Anatomical (CT) and functional (PET) data for cancer diagnosis. Despite advancements in machine learning for automated medical image analysis, publicly available PET/CT datasets remain scarce, limiting Artificial Intelligence (AI) research compared to CT and MRI. This study built a publicly accessible PET/CT Vietnamese dataset for Non-Small Cell Lung Cancer (NSCLC). A total of 416 PET/CT scans were collected from three Vietnamese hospitals, including 300 NSCLC cases. Malignant FDG-sensitive lesions, identified via clinical PET/CT reports, were manually segmented in 3D (slice-by-slice) on PET images and validated by three experienced radiologists. The dataset includes both original and annotated DICOM files, along with clinical patient data. It achieved a dice similarity coefficient of 80.3 % and volume similarity of 81.9 %, demonstrating high segmentation accuracy comparable to other studies. This dataset supports AI-driven NSCLC research and contributes to global efforts in automated PET/CT analysis for nuclear medicine applications.
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