Muhammadiyah Medical Journal
Vol. 6 No. 1 (2025): Muhammadiyah Medical Journal (MMJ)

Clinical Features of Pulmonary Tuberculosis Patients Performing Molecular Rapid Test at Jakarta Islamic Hospital Cempaka Putih

Shabrina, Fida Alia (Unknown)
Rayhana, Rayhana (Unknown)
Wahyuni, Tri (Unknown)



Article Info

Publish Date
21 Jul 2025

Abstract

Background: Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis. This germ has a dormant phase, which causes the healing process to take a long time, thereby increasing the risk of discontinuing drug consumption in TB patients. This has resulted in resistance to several types of anti-tuberculosis drugs, one of which is Rifampicin, a first-line drug in TB treatment. Rifampicin-resistant TB (RR-TB) requires rapid and precise diagnosis and treatment, namely the PCR method using the GeneXpert tool. Purposes: To find out the clinical features of pulmonary tuberculosis patients performing TCM GeneXpert at the Jakarta Islamic Hospital Cempaka Putih in January – June 2022. Methods: This study employs a descriptive observational method, which describes a clinical feature based on secondary data (medical records) from adult pulmonary TB patients undergoing TCM at RSIJ Cempaka Putih. Results: Among patients examined by Molecular Rapid Test, 64 individuals (59.3%) were MTB-detected, and among them, 12 individuals (18.8%) had rifampicin resistance. The highest positivity value from the results of MTB-detected was MTB-Medium Detected, namely 11 people (10.2%). The most common clinical symptom in pulmonary TB patients was cough with phlegm, which was 67 people (62%), and the comorbidity that most patients suffered was diabetes mellitus, which was 21 people (19.4%). Conclusions: The frequency distribution of the Molecular Rapid Test (MRT) results showed that 59.3% of the MTB-detected cases were rifampicin-resistant, with 18.8% of the total. Cough with phlegm is the most common clinical symptom experienced by TB patients, namely 62%.

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Journal Info

Abbrev

MMJ

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Description

Muhammadiyah Medical Journal (MMJ) Faculty of Medicine and Health is an international journal based on scientific research. The journal is published 2 (two) times in 1 year, March and September. Muhammadiyah Medical Journal Faculty of Medicine and Health invites the lecturers, practitioners and ...