<![CDATA[Background: Liver cirrhosis is a chronic liver disease characterized by fibrosis and replacement of normal liver tissue with abnormal nodules. The main etiologies include hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, alcohol-related liver disease, and non-alcoholic fatty liver disease (NAFLD). The prevalence of liver cirrhosis based on autopsy findings is around 2.4% in Western countries, while in the United States it is estimated at 360 per 100,000 population, causing approximately 35,000 deaths annually. Objective: This case report aims to describe the treatment and identify drug-related problems (DRPs) in a patient diagnosed with PNSD CTP B liver cirrhosis, chronic hepatitis B, dyspepsia syndrome, hypoalbuminemia, and impaired liver function. Method: This study employed a case report design with primary data obtained from patient interviews and retrospective documentation review. Data were analyzed using the SOAP method to identify DRPs. Results: The analysis revealed minor drug interactions, including spironolactone–furosemide, tenofovir disoproxil fumarate (TDF)–morphine sulfate tablet (MST), and cefixime–furosemide. Conclusion: Patients with complex comorbidities are at increased risk of DRPs. Continuous pharmacotherapy monitoring is essential to minimize toxicity and adverse effects.]]>
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