The Somali region of Ethiopia, predominantly inhabited by pastoralists, faces serious threats to food security and economy from livestock diseases. Among these diseases, Peste des Petits Ruminants (PPR) and Contagious Caprine Pleuropneumonia (CCPP) are of major concern, especially in small ruminants such as goats, with high morbidity and mortality rates. To evaluate the impact of treatment interventions (administration of 20% oxytetracycline and Penistripe) and mass vaccination campaigns on the morbidity and mortality rates caused by PPR and CCPP outbreaks. The research method will focus on the epidemiological analysis of concurrent PPR and CCPP outbreaks in Jarar and Doollo Zones, Somali Region, Ethiopia in February 2025, by reviewing laboratory confirmation data and responses to interventions. The study will also evaluate the effectiveness of antibiotic treatment and mass vaccination campaigns in controlling the spread of diseases in small ruminants in the region. The research results showed that the detection of PPR Ag in the nasal discharge of infected caprine provided strong evidence of active PPR infection, also the detection of CCPP antibodies in the serum of infected caprine showed clearly active for CCPP infection. The research conclusion is that successfully control the spread of PPR, immediate intervention measures are mandatory, such as vaccinations campaigns, isolation of sick and healthy animals and treatment of infected animals are imperative.
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