Eduvest - Journal of Universal Studies
Vol. 5 No. 9 (2025): Eduvest - Journal of Universal Studies

Relationship of 25 Hydroxyvitamin D Levels with C-Telopeptide Levels in Perimenopausal Women

T. Sumarlin (Universitas Sam Ratulangi, Indonesia)
Eddy Suparman (Universitas Sam Ratulangi, Indonesia)
Hermie M. M. Tendean (Universitas Sam Ratulangi, Indonesia)



Article Info

Publish Date
24 Sep 2025

Abstract

Osteoporosis represents a significant global health challenge, particularly affecting perimenopausal women who experience accelerated bone loss due to declining estrogen levels. The relationship between vitamin D status and bone turnover markers during this critical transition period requires further investigation to optimize preventive strategies. This study [A1] aims to examine the relationship between 25-Hydroxyvitamin D (25(OH)D) and C-Telopeptide (CTx) levels in perimenopausal women in Manado. Vitamin D has an important role in maintaining bone health, and its deficiency can have an impact on a variety of health problems. This cross-sectional study involved 30 participants from Prof. Dr. R.D. Kandou Hospital and network hospitals in Manado. The results showed that 50% of the respondents had sufficient levels of 25(OH)D, while the remaining 50% were in the deficient category. The average level of 25(OH)D was 30.30 ng/mL. For CTx, 60% of respondents were at high risk and the remaining 40% were at low risk, with an average of 0.67 ng/mL. However, a non-parametric correlation test (Spearman's rho) between 25(OH)D and CTx showed statistically insignificant results (r=0.024; p=0.902). Therefore, this study concluded that there was no statistically significant relationship between 25(OH)D and CTx levels in perimenopausal women in the sample studied.

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Journal Info

Abbrev

edv

Publisher

Subject

Aerospace Engineering Computer Science & IT Health Professions Neuroscience Social Sciences

Description

Eduvest - Journal of Universal Studies is a double blind peer-reviewed academic journal and open access to multidiciplinary fields. The journal is published monthly by Green Publisher Indonesia. Eduvest - Journal of Universal Studies provides a means for sustained discussion of relevant issues that ...