Indonesian Journal of Chemical Science and Technology
Vol. 8 No. 2 (2025): JULY 2025

Antioxidant activity of local Gompang Batu Plants (Lobelia nummularia Lam) in vitro DPPH Method

Ester Basani Panggabean (Unknown)
Murniaty Simorangkir (Unknown)



Article Info

Publish Date
27 Aug 2025

Abstract

Free radicals are reactive atoms or molecules because they contain unpaired electrons that easily attack body structures, causing various diseases such as cancer, liver, heart and other degenerative diseases. Antioxidants are compounds or molecules that can reduce free radicals. Natural antioxidants are needed to reduce the effects of using synthetic antioxidants. The local plant gompang batu (Lobelia nummularia Lam) is found in Ruhut Bosi Village, Pangaribuan District and has been used by the community as a traditional medicine. This study aims to determine the content of secondary metabolites and antioxidant activity of ethanol extract of gompang batu in vitro using the DPPH (2,2 diphenyl-1-picrylhydrazyl) method. The results of the phytochemical screening test of the gompang batu plant contain secondary metabolites of flavonoids, alkaloids, steroids/terpenoids and saponins. The results of the antioxidant activity test of the ethanol extract of gompang batu obtained an IC50 value of 135,095 ppm (moderate category) and an IC50 value of vitamin C (as a positive control) of 39,390 ppm.

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Journal Info

Abbrev

aromatika

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology

Description

Jurnal ini mempublikasikan artikel di bidang Kimia yang meliputi penelitian dasar dan terapan. Bentuk Publikasi di Indonesian Journal of Chemical Science and Technology : * Artikel * Review (berdasarkan permintaan Dewan Redaksi) * Communication (berdasarkan permintaan Dewan ...