The metamorphosis of Islamic Education Institution such as IAIN into UIN has brought consequences, i. e. objectification of social sciences to Islamic value. This includes themes in social work discipline; as a science or as a profession. This article argues that prophetic institutionalization is crucial and significant in adjusting with challenges regarding not only as academic but also as practical purposes. Through a qualitative approach, several Islamic basic principles found that may serve as a guiding principle of general and specific themes in social work science, among general aspects are rahmatan lil ‘alamin, al-‘Amal al-Shalih, al-Ikhlas, empowerment of vurnerable group (mustadh’afin), while the specific consists of ta’awwun, tawashshou, amr ma’ruf nahi munkar, sadaqa, covering one’s ‘aib and tawakkal. Keywords: Objectivation, Islam and Social Work
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