Pharmacon
Vol 21, Special Issue 1, 2024

Formulation and Characterization of Gels of Telang Flower Extract (Clitoria Ternatea L) with Variations of Carbopol Concentration and Antioxidant Activity Test Using DPPH Methods

Nurwaini, Setyo (Unknown)
Fatimah, Mutiara Nurul (Unknown)



Article Info

Publish Date
08 Apr 2024

Abstract

Telang flower (Clitoria ternatea L) has antioxidant activity. Formulation in gel form provides convenience in the use of telang flower extract. This study aims to determine the effect of carbopol as a gelling agent on the physical properties of the gel and to determine the antioxidant activity of telang flower extract gel. Telang flower extract was obtained by maceration method. The gel was formulated with 3 variations of carbopol concentration, namely 0.5%, 1% and 2%. Characterization of Clitoria ternatea L. gel includes: organoleptic, homogeneity, pH, viscosity, spreadability and stickiness. Antioxidant activity test of telang flower (Clitoria ternatea L) using DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The gel formulation of telang flower extract (Clitoria ternatea L.) from 3 formulas met the requirements. Gel with 2% carbopol concentration was the gel with the best characteristics: pH 5.82; viscosity 2,666 cP; spreadability 4.33 cm; stickiness 2.2 s. The Antioxidant activity test of telang flower extract gel showed strong category with an IC50 value of 97.72 ppm. Carbopol has an influence on the physical properties of telang flower extract (Clitoria ternatea L) gel and strong antioxidant activity of bay flower extract gel.

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Journal Info

Abbrev

pharmacon

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Pharmacon: Jurnal Farmasi Indonesia is a collection of publication journals, covering all aspects of Pharmaceutical sciences, including Technology of Formulations, Excipients Optimization, Extract and Herbal Standardizations, Pharmacological activity determination on natural sources, Drug Synthesize ...