Eduvest - Journal of Universal Studies
Vol. 5 No. 8 (2025): Eduvest - Journal of Universal Studies

The Relationship Between Medication Adherence, Antipsychotic Side Effects, and Quality of Life in Schizophrenia Patients: An Evaluation Using Mars10, Gass, and SQLS

Mariance Trisnawati (Universitas 17 Agustus 1945 Jakarta, Indonesia)
Sylvia Rizki Prima (Universitas 17 Agustus 1945 Jakarta, Indonesia)



Article Info

Publish Date
12 Aug 2025

Abstract

This study aimed to analyze the relationship between medication adherence, antipsychotic side effects and quality of life in schizophrenic patients. A total of 263 respondents participated in this study using three validated instruments: the Medication Adherence Rating Scale (MARS-10), the Glasgow Antipsychotic Side-effect Scale (GASS), and the Schizophrenia Quality of Life Scale (SQLS). The results of the analysis showed a very significant positive correlation between medication adherence and patient quality of life (r = 0.808; p = 0.000). In contrast, no significant association was found between antipsychotic side effects and adherence (r = -0.003; p = 0.956) or quality of life (r = -0.028; p = 0.649). The three instruments used showed high reliability with Cronbach's Alpha values of 0.941 (MARS-10), 0.970 (GASS), and 0.981 (SQLS), respectively. These findings confirm the importance of interventions aimed at improving medication adherence as a key strategy in improving the quality of life of schizophrenic patients. Further research recommends for future patient-centered approaches, ongoing education, strong family involvement and therapeutic relationships, as well as the need for social support from other psychosocial factors.

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Journal Info

Abbrev

edv

Publisher

Subject

Aerospace Engineering Computer Science & IT Health Professions Neuroscience Social Sciences

Description

Eduvest - Journal of Universal Studies is a double blind peer-reviewed academic journal and open access to multidiciplinary fields. The journal is published monthly by Green Publisher Indonesia. Eduvest - Journal of Universal Studies provides a means for sustained discussion of relevant issues that ...