Indonesian Journal of Urology
Vol 32 No 1 (2025)

THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Hamzah, Moh. Alwi (Unknown)
Muhammad Risan (Unknown)
Muhammad Jabir (Unknown)



Article Info

Publish Date
02 Jan 2025

Abstract

Objective: This systematic review aims to determine the efficacy and safety of topical triamcinolone in reducing urethral stricture recurrence following internal urethrotomy procedures. Material & Methods: A systematic literature search was performed in Cochrane Library, PubMed and Google Scholar with the related keywords. The statistical analysis was conducted using a Review Manager v.5.4.1. Results: We identified 6 RCTs with a total of 316 patients diagnosed with urethral stricture undergoing internal urethrotomy. The statistical analysis appeared to lower the recurrence rate significantly in patients undergoing internal urethrotomy with the adjuvant therapy of topical triamcinolone (RR 0.55, 95% CI 0.38 – 0.78, p = 0.0008). Conclusion: Additional treatment with topical triamcinolone has the benefit of declining the recurrence rate of urethral stricture following internal urethrotomy. Keywords: Triamcinolone, urethral stricture, internal urethrotomy.

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Journal Info

Abbrev

juri

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

The aim of Indonesian Journal of Urology is to encompass the whole spectrum of urology. The journal publishes papers on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, pediatric ...