Introduction: Giant cell tumor of bone (GCTB) is a rare, benign but locally aggressive tumor that uncommonly afects distal ulna. Case: This case is a 30-year-old female with worsening pain, swelling, and limited wrist motion. Imaging studies revealed cortical destruction and soft tissue infltration characteristic of an aggressive GCTB. Campanacci type 3 GCTB of the distal ulna was diagnosed and managed through limb salvage surgery using a combination of Darrach procedure and single bone technique.This combined approach aims to achieve tumor clearance while preserving limb function. Post-operative management included soft tissue closure using an abdominal fap. Conclusion: The case highlights the challenges in managing aggressive GCTBs of the distal ulna and demonstrates a viable limb salvage strategy. Long-term follow-up is recommended to evaluate functional outcomes and to monitor for recurrence, because tumor’s aggressive nature.
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