This study was carried out to determine the level of C-reactive protein (CRP) in Urinary Tract infection Patients attending Madonna University Teaching Hospital. C- reactive protein was measured using the ELISA (Enzyme-Linked Immunosorbent Assay) method. The statistical software for social sciences (SPSS) version 26 was used to statistically analyze the data acquired from this study. C- reactive protein values in the UTI group (20.75±8.35 mg/L) were significantly higher than those in the control group (3.08±1.28 mg/L), demonstrating a strong inflammatory response to UTIs. Additionally, age-related study showed that children and adolescents had greater CRP levels than adults. Patients with Escherichia coli showed considerably higher CRP levels than Klebsiella pneumoniae and Proteus mirabilis in the bacterial growth categories, however no significant difference was seen between Klebsiella pneumoniae and Proteus mirabilis. Differences in immune response dynamics, pathogen pathogenicity, and host-pathogen interactions can be used to explain these variances in CRP levels. The results show how useful CRP is as an inflammatory marker in UTIs.
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