AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh
Averrous, Volume 11 No.2 November 2025

Comparative In Vitro Study of Cinnamon (Cinnamomum burmannii) Extract and Ciprofloxacin on the Inhibition of Escherichia coli Growth Causing Urinary Tract Infection

Milala, Alvin Nugraha S. (Unknown)
Nasution, Sri Wahyuni (Unknown)
Rusip, Gusbakti (Unknown)



Article Info

Publish Date
18 Nov 2025

Abstract

Cinnamon (Cinnamomum burmannii) contains various bioactive compounds, primarily cinnamaldehyde and eugenol, which are known for their antibacterial properties. The increasing resistance of Escherichia coli to conventional antibiotics highlights the need for developing effective natural alternatives with antimicrobial potential.This study aimed to determine the antibacterial effectiveness of cinnamon extract compared to ciprofloxacin in inhibiting the growth of Escherichia coli.This research was an experimental laboratory study using the disc diffusion method to measure antibacterial activity.The results showed that cinnamon extract was capable of inhibiting Escherichia coli growth, with mean inhibition zone diameters of 11.84 mm at 25%, 13.94 mm at 50%, 17.52 mm at 75%, and 15.79 mm at 100% concentrations. In comparison, ciprofloxacin produced an inhibition zone of 18.37 mm, aquadest showed no inhibitory effect.Cinnamon extract demonstrated antibacterial activity against Escherichia coli, with the highest effectiveness observed at a concentration of 75%, although its inhibitory power remained lower than that of ciprofloxacin.

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Journal Info

Abbrev

averrous

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

Averrous: Jurnal Kedokteran dan Kesehatan Malikussaleh (Averrous: Malikussaleh Journal of Medicine and Health - Averrous: MJMH*) is a peer-reviewed and open-access journal. Publishes by the Faculty of Medicine Universitas Malikussaleh in collaboration with the Institute for Research and Community ...