<![CDATA[Oral infections caused by Streptococcus mutans and Porphyromonas gingivalis are common health problems. This in vitro study aimed to evaluate the antibacterial activity of Pandanus nut (Pandanus julianettii) with n-hexane and ethyl acetate fractions against these pathogens through agar diffusion assays. The n-hexane and ethyl acetate fractions were subjected to agar diffusion testing, with Minimum Inhibitory Concentration (MIC) values determined at 0.8% and 0.2% respectively against both bacterial strains. Subsequent Minimum Bactericidal Concentration (MBC) testing revealed values of 6.4-12.8% for n-hexane fraction and 3.2-6.4% for ethyl acetate fraction. In agar diffusion assays, the n-hexane fraction at 12.8% concentration produced inhibition zones of 15.54±0,20 mm on S. mutans and 15.46±0,35 mm on P. gingivalis. The ethyl acetate fraction showed significantly larger inhibition zones of 18.76±0,79 mm against S. mutans and 15.59±0,42 mm against P. gingivalis at the same concentration. These findings demonstrate that both n-hexane and ethyl acetate fractions of Pandanus nut possess substantial antibacterial activity against oral pathogens.]]>
Copyrights © 2025
