PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Vol. 3 No. 1 (2024): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA

Uji Efektifitas ekstrak Daun Beluntas (Plucea indica L.) Untuk Kelancaran Pengeluaran ASI Pada Masa Menyusui Tikus Galur Wistar (Rattus Norvegicus) Betina

Fransiskus Aryo Pratomo (Unknown)



Article Info

Publish Date
30 May 2024

Abstract

This study aimed to evaluate the effectiveness of Pluchea indica (beluntas) leaf extract in promoting breast milk secretion during the lactation period in female Wistar rats (Rattus norvegicus). The experimental research was conducted at Universitas Adiwangsa Jambi using 24 lactating rats, randomly assigned into four groups: a negative control group (distilled water), a positive control group (commercial lactation booster), and two treatment groups receiving Pluchea indica extract at doses of 200 mg/kg BW and 400 mg/kg BW, respectively. The treatment was administered for 14 consecutive days during the lactation period. Parameters observed included the body weight gain of the pups as an indirect indicator of milk production, along with maternal nursing behavior and physiological conditions.The results demonstrated that administration of Pluchea indica extract, particularly at 400 mg/kg BW, significantly increased (p<0.05) pup body weight compared to the negative control group and showed comparable effectiveness to the positive control group. No signs of toxicity or disruption in maternal behavior were observed throughout the study. In conclusion, Pluchea indica leaf extract shows potential as a natural galactagogue agent that effectively enhances milk production, and it may serve as a promising phytopharmaceutical candidate to support maternal lactation health.

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Journal Info

Abbrev

pharm

Publisher

Subject

Medicine & Pharmacology

Description

Pharmanaja : Pharmaceutical Journal of Unaja merupakan jurnal elektronik yang dikelola Program Studi Farmasi Universitas Adiwangsa Jambi. jurnal ini merupakan media publikasi hasil penelitian dan review artikel pada semua aspek ilmu Farmasi yang bersifat inovatif, kreatif, Original, dan didasarkan ...