<![CDATA[Coccidiosis is a parasitic disease that commonly affects broiler chickens, caused by protozoa of the genus Eimeria. This disease significantly reduces productivity, impairs feed efficiency, and increases mortality rates. The continuous use of synthetic anticoccidial drugs has raised concerns over resistance and drug residues accumulation in poultry products. This study aimed to evaluate and compare the in vitro anticoccidial efficacy of herbal powders from Andrographis paniculata (sambiloto) and Morinda citrifolia (noni leaves) as potential natural alternatives. A total of 150 fecal samples were collected from five poultry farms using a simple random sampling method. Eight treatment groups were established: a negative control (without coccidiostat), a positive control (trimethoprim-sulfamethoxazole), and six herbal treatments (0.25%, 0.5% and 0.75% of both A. paniculata and M. citrifolia powders). Each treatment group comprised five biological replicates. Oocyst per gram (OPG) counts were determined using McMaster technique. Both herbal powders significantly reduced OPG compared to the negative control (p < 0.05). The most effective treatment was M. citrifolia at 0.75%, showing the lowest OPG value and comparable efficacy to the synthetic anticoccidial. M. citrifolia 0.75% reduced mean OPG to 4,098 ± 250 (p < 0.001) compared to the negative control. This study provides the direct comparative evidence of A. paniculata and M. citrifolia anticoccidial activity using standardized OPG quantification, suggesting their promise as sustainable herbal alternatives for coccidiosis control.]]>
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