Journal of Embedded Systems, Security and Intelligent Systems
Vol 6, No 3 (2025): September 2025

AI-Powered Botox Dosage Classification: A Comparative Study of CNN Architectures on Facial Wrinkle Analysis

Ayutri Wahyuni (Unknown)
Resky Ayu Dewi Talasari (Unknown)



Article Info

Publish Date
18 Oct 2025

Abstract

Botulinum Toxin (BOTOX) injections are widely used as a non-invasive cosmetic treatment to enhance facial appearance. However, determining the optimal dosage still relies on subjective visual assessment by medical professionals, which can lead to inconsistency. This study proposes a model deep learning–based classification framework using convolutional neural networks (CNNs) to automate BOTOX dosage prediction from forehead wrinkle images. Four CNN architectures Inception-V3, ResNet-34, ResNet101-V2, and EfficientNetB2 were evaluated on an augmented dataset of 168 cropped images, equally divided between 2-unit and 4-unit dosages. The dataset was generated through flipping and rotation augmentation to address class imbalance and enhance model generalization. Among the models, EfficientNetB2 achieved the highest accuracy of 92.8%, surpassing Inception-V3 85.7%, ResNet-34 82.1%, and ResNet101-V2 80.3%. The superior performance of EfficientNetB2 reflects its capability to extract fine-grained wrinkle patterns efficiently while maintaining computational efficiency. The novelty of this work lies in integrating CNN-based visual feature extraction with expert-labeled clinical image data for objective BOTOX dosage determination. Although limited by dataset size, this study highlights the potential clinical application of deep learning in supporting accurate, consistent, and data-driven facial aesthetic treatments.

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Journal Info

Abbrev

JESSI

Publisher

Subject

Computer Science & IT

Description

The Journal of Embedded System Security and Intelligent System (JESSI), ISSN/e-ISSN 2745-925X/2722-273X covers all topics of technology in the field of embedded system, computer and network security, and intelligence system as well as innovative and productive ideas related to emerging technology ...