Academic Letters
Vol 1 No 6 (2025)

Peanut: Relationship, Arginine, and Cardiovascular Health

Sutrisno Adi Prayitno (Food Technology Study Program, Universitas Muhammadiyah Gresik, East Java 61121)
Andalusia Trisna Salsabila (Food Technology Study Program, Universitas Muhammadiyah Gresik, East Java 61121)
Devi Kartika Sari (Food Technology Study Program, Universitas Muhammadiyah Gresik, East Java 61121)



Article Info

Publish Date
02 Nov 2025

Abstract

Peanuts (Arachis hypogaea L.) are nutrient-dense legumes that play an important role in global food systems and human health. Beyond serving as an affordable source of energy and plant-based protein, peanuts are increasingly recognized as a functional food due to their rich content of unsaturated fatty acids, dietary fiber, minerals, phytosterols, and polyphenolic compounds associated with reduced cardiovascular disease (CVD) risk. Among these components, arginine—a semi-essential amino acid abundantly present in peanuts—has received considerable attention for its role in nitric oxide (NO) synthesis and vascular health. Arginine-derived NO is a key regulator of endothelial function, blood pressure, and platelet aggregation, and impaired NO bioavailability is closely linked to hypertension and atherosclerosis. Evidence from randomized controlled trials and meta-analyses published between 2020 and 2024 indicates that regular peanut consumption is associated with improvements in lipid profiles, inflammatory markers, and overall cardiometabolic health, particularly in individuals with metabolic disorders. The cardioprotective effects of peanuts are mediated through synergistic interactions between arginine, unsaturated fats, phytosterols, dietary fiber, and antioxidant compounds. Collectively, these findings support the inclusion of peanuts in balanced dietary patterns aimed at cardiovascular disease prevention.

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Journal Info

Abbrev

academic-letters

Publisher

Subject

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Other

Description

Academic Letters is a new experiment in open access academic publishing. We aim to publish short-form articles such as brief reports, case studies, reports of new findings, socio-political critiques, credible scholarly opinions, and ideas omitted from previously published works. Articles published ...