SIMBIOSIS
Simbiosis Volume 12 No. 1 2024

LAMA WAKTU PENGHENTIAN KONSUMSI SOJU TERHADAP KADAR ALKOHOL HATI, MORFOLOGI HATI, DAN GAMBARAN HEMATOLOGI TIKUS PUTIH

Tiffany Angelita Putri Mileva (Mahasiswa PS Biologi FMIPA UNUD)
Ni Wayan Sudatri (Lab Fisiologi Hewan, PS Biologi FMIPA UNUD)
I Made Sara Wijana (Lab Biokimia PS Biologi FMIPA UNUD)



Article Info

Publish Date
02 Apr 2024

Abstract

Alcohol consumption behaviors such as soju can increase metabolic syndrome disease. The elimination of alcohol in the body can determine the last time a person consumed alcohol through post-absorption assessment of alcohol. This study was conducted to determine changes in liver macroscopic morphology, liver alcohol levels and hematological features after stopping soju administration in white rats. The research design used was a complete randomized design with 4 treatments, namely the examination time P(0) 0 days, P(1) 3 days, P(2) 7 days, and P(3) 10 days. The methods used in this study are liver weight weighing, observation of macroscopic morphological conditions of the liver, examination of alcohol levels with gas chromatography-flame ionization detector and hematological examination with haematology analyzer. The results showed that stopping soju for 10 days had a significant effect on reducing liver weight and reducing fatty liver, decreased alcohol levels, red blood cell count, PCV percentage and hemoglobin levels that returned to the normal range. While the number of white blood cells does not show any influence and the value is below the normal range. Keywords: alcohol, liver, blood profile, soju, white rat

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Journal Info

Abbrev

simbiosis

Publisher

Subject

Biochemistry, Genetics & Molecular Biology

Description

Simbiosis (e ISSN: 2337-7224))is an electronic scientific journal published periodically by the Biology Under Graduade Program, Faculty of basic and Natural Sciences, Udayana University , containing scientific works biology that include botany, zoology, microbiology, and molecular genetics and the ...