International Journal of Health, Economics, and Social Sciences (IJHESS)
Vol. 8 No. 1: Januari 2026

Literature Review: Physical Stability Evaluation of Various Natural Extract-Based Preparations

Ines Septiani Pratiwi (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Retno Wahyuningrum (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Ika Lismayani Ilyas (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Auliah Usman (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Putri Ramadani Ridwan (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Mirna (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Zafirah Sarif (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Nur Fadilah (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Ildhy Alzari Ashar (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Shintya Dewi Pratiwi (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Anisa Ramadhani (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Infahna (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)
Syalda Syahifni Rum (Jurusan Farmasi, Fakultas Sains dan Teknologi, Universitas Sembilanbelas November Kolaka, Jl. Ahmad Mustin - Kolaka)



Article Info

Publish Date
10 Jan 2026

Abstract

This literature review examines the physical stability of various natural extract-based preparations increasingly used in cosmetic and pharmaceutical formulations. The main problem identified is the high phytochemical variation of the extracts, which can affect physical stability, such as changes in pH, viscosity, homogeneity, color, and texture during storage. The purpose of this study was to analyze physical stability parameters in various dosage forms, such as liquid, semi-solid, and solid, and to evaluate factors influencing their instability, based on selected literature from 2020 to 2025. The method used was a literature review through an online search of national and international journals relevant to the available data. Ten articles were used to support this literature review. The results of the literature review indicate that liquid dosage forms tend to be susceptible to organoleptic and clarity changes, while semi-solid dosage forms are strongly influenced by the stability of polymer matrices and emulsions, while solid dosage forms have the best stability due to their low water content. Based on the results of this literature review, it can be concluded that the physical stability of a preparation is highly dependent on the suitability of the excipients, the characteristics of the extract, and the stability testing method used. This review is expected to serve as a reference in the development of more stable and high-quality natural ingredient extract formulations.

Copyrights © 2026






Journal Info

Abbrev

IJHESS

Publisher

Subject

Economics, Econometrics & Finance Public Health Social Sciences

Description

nternational Journal of Health, Economics, and Social Sciences (IJHESS) is a peer-reviewed electronic international journal. This statement clarifies ethical behaviour of all parties involved in the act of publishing an article in this journal, including the author, the chief editor, the Editorial ...