<![CDATA[Laminectomy is an orthopedic procedure that can cause moderate to severe postoperative pain, making perioperative opioid use a common choice. However, excessive opioid administration increases the risk of adverse effects and dependency. Multimodal analgesia is designed to reduce opioid consumption by combining several analgesic agents with different mechanisms of action. Objective: To evaluate the use of multimodal analgesia and the need for opioids during general anesthesia in patients undergoing laminectomy. Methods: This study is a descriptive observational case series involving five patients who underwent laminectomy at RSUD dr. Soedono Madiun. Data collected included the types of multimodal analgesics administered, intraoperative opioid use, and hemodynamic stability throughout the procedure. Results: All patients received preoperative multimodal analgesia consisting of paracetamol, NSAIDs (dexketoprofen/ketorolac), corticosteroids (dexamethasone), and ketamine in selected cases. Intraoperative opioid use was reduced, with relatively low total doses of fentanyl or sufentanil administered across cases. Overall, patient hemodynamics remained stable, with minimal fluctuations associated with opioid or anesthetic effects. Conclusion:The application of multimodal analgesia in laminectomy effectively managed perioperative pain while reducing opioid requirements during general anesthesia. This strategy proved beneficial and safe, supporting postoperative recovery with fewer opioid-related risks.]]>
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