Axiology is a branch of the philosophy of science that examines values, ethics, and aesthetics as normative foundations in the development and application of scientific knowledge. This article aims to analyze the values and ethics of science from the perspective of axiology in the philosophy of science and to emphasize the importance of moral and social responsibility in scientific practice. This study employs a qualitative approach using library research by critically reviewing relevant books and scholarly articles. The findings indicate that axiology plays a significant role in determining the direction and usefulness of science so that it is not only oriented toward truth and intellectual progress, but also toward human welfare. Ethics functions as a moral guideline for scientific behavior and the application of knowledge in accordance with social and cultural norms, while aesthetics complements ethical considerations through values of beauty, order, and harmony in human works. Values in science are subjective and contextual, depending on humans as valuing subjects. Therefore, the development and application of scientific knowledge must be accompanied by ethical awareness and social responsibility to ensure positive contributions to human life and society.
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