Introduction: Dyspepsia is one of the common but nonspecific medical complaint sought by adult population. It accounts for about 2-5% of all primary care consultations among adults and approximately 20 to 25 percent of patients with dyspepsia have an underlying organic cause. Evaluation of dyspepsia is important in view of the infective or neoplastic etiology in some cases thereby enabling the clinician or gastroenterologist to institute the cause specific treatment. This study was conducted in SMHS hospital of GMC Srinagar to evaluate the clinical and etiological features of patients with dyspepsia Aim and objective: To evaluate clinically the patients with dyspepsia and to establish the cause of dyspepsia by endoscopic examination. Study Design: This prospective observational hospital based study was conducted in the Department of General Medicine in collaboration with the Department of Gastroentrology and Hepatology, Government Medical College Srinagar, a tertiary health care centre in Kashmir over a period of one and half years. Patient with one or more of the symptoms like bothersome postprandial fullness, early satiation, epigastric pain , epigastric burning last more than 4 weeks and ≥18 years of age were included in the study. Patients with Age < 18 years, hemodynamicaly unstable patients, patients with history of upper GI surgery and radiation exposure were excluded. The patients underwent history, clinical examaination, baseline line investigations, Upper GI endoscopy, urea breath test and other relevant tests as required. Data was collected and evaluated with respect to the clinical findings and Upper GI endoscopy and urea breath test findings. Results: In this study a total of 600 patients were enrolled. The mean age of male patients was 50.4+14.4 years and 45.8+10.6 years in females. Most common comorbid illness was hypertension in 112 (18.67%) patients followed by diabetes mellitus in 104 (17.34%) and hypothyroidism in 74 (12.33%) patients. Most common EGD finding was antral gastritis observed in 252 (42%) patients in which non-erosive antral gastritis was seen in 210 (35%) and erosive antral gastritis in 42 (7%), malignancy, gastric polyp and gastroduodenitis were observed in 14 (2.33%) patients each besides other causes. Rapid urease test was done in 40 patients in which 33 (82.5%) were positive for H. pylori. Out of these 33 patients, 24 (72.7%) were having erosive gastritis, 6 (18.18%) had duodenal ulcer and 3 (9.9%) were normal on EGD. Conclusion: We conclude that UGI endoscopy being a simple procedure should be undertaken for early diagnosis of benign as well as malignant lesions in patient presenting with dyspepsia especially in those not responding to treatment.
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