Nusantara Medical Science Journal
Vol. 10 No. 2 (2025): Volume 10 Issue 2, July - December 2025

Evaluation of Systemic Immune-Inflammation Index for Predicting Mortality in Sepsis Patients

Haizah Nurdin (Unknown)
Salam, Syamsul Hilal (Unknown)
Tanra, Andi Husni (Unknown)
Palinrungi, Ari Santri (Unknown)
Sulkifli Mangga Barani, A.M. Irsyad (Unknown)
Faisal Muchtar (Unknown)



Article Info

Publish Date
02 Jan 2026

Abstract

Introduction: This study aims to measure the accuracy of Systemic Immune-Inflammation Index (SII) in predicting 28-day mortality in sepsis patients in intensive care unit. Methods:   This study was conducted as a retrospective cohort study. The study was conducted in the intensive care unit of Dr. Wahidin Sudirohusodo General Hospital. The study subjects consisted of all sepsis patients admitted to the intensive care unit during the period January 2023 to December 2023 who met the inclusion criteria. Results:  Total sample is 147 participants. Systemic Immune-Inflammation Index (SII) showed a significant difference in predicting sepsis mortality. SII has an AUC value of 0.763 with a sensitivity of 69.6% and a specificity of 71.1% at a cut-off of 2003.395. Conclusions: Systemic Immune-Inflammation Index (SII) scores are associated with increased mortality in sepsis patients in the intensive care unit of Dr. Wahidin Sudirohusodo Hospital. The SII can be a prediction tool in clinical practice in predicting mortality of sepsis patients.  

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Journal Info

Abbrev

jmednus

Publisher

Subject

Materials Science & Nanotechnology Neuroscience

Description

Nusantara Medical Science Journal (NMSJ) is an open access, peer-reviewed journal published by Faculty of Medicine, Hasanuddin University twice a year in June and December. NMSJ encompasses all basic and molecular aspects of medical sciences, with an emphasis on the molecular studies of biomedical ...