It is expensive to transmit or store significant amounts of electrocardiogram (ECG) records, particularly when using telecommunications channels that charge according to the volume of transferred data. The advancement of telemedicine renders compressing ECG signals even more necessary. Compression aims to reduce the size of data while maintaining the features of ECG signals. This paper presents a novel strategy for compressing ECG signals based on 3D format conversion. After identifying the RR intervals, we divide the signal into cardiac cycles and proceed with the cut and align process. A 3D discrete wavelet transform (DWT) is employed to minimize the correlation existing between two adjacent voxels. Moreover, an optimized run-length encoding (RLE), a novel lossless compression technique, has been proposed to increase the compression ratio (CR). The proposed strategy is applied to different types of ECG records of the Arryyhmia database. This algorithm demonstrates improved performance in terms of CR and percentage root-mean-square difference (PRD) compared to several recently published works.
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