Medicinus : Jurnal Kedokteran
Vol. 15 No. 1 (2025): October

A Rare Manifestation of ‘Complex’ Post Streptococcus Infection Movement Disorder in Paediatric Patient a Case Report

Lalisang, Lilie (Unknown)
Khairani, Arie (Unknown)
Chairy, Abdul (Unknown)
Djuanda, Gerald (Unknown)



Article Info

Publish Date
01 Oct 2025

Abstract

Background: Post Streptococcal Movement Disorder (PSMD) is a rare disease. One of the PSMD diagnosis is Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infection (PANDAS). Case Description: 10 year old female with involuntary movement including myoclonic jerks, chorea and stereotype. Movement duration is 5 minutes, repetitive and sensitive to loud noise. Patient has history of respiratory infection 2 weeks ago with Positive ASTO test. Patients showed improvement after treatment with antibiotics, corticosteroids and antipsychotics. Conclusion: The pathophysiology of PANDAS begins with Group A beta-hemolytic infection that causes cross reaction in cortical structures and basal ganglia due to molecular mimicry. Currently there is no definitive test for PANDAS,where diagnosis is primarly confirmed by identifying signs, symptoms and physical neurological examination.

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Journal Info

Abbrev

Medicinus : Jurnal Kedokteran

Publisher

Subject

Medicine & Pharmacology Public Health

Description

Medicinus: Jurnal Kedokteran is an official journal of the Faculty of Medicine, Universitas Pelita Harapan launched in the year 2007. Medicinus is a peer-reviewed and open-access journal that covers basic, translational, or clinical aspects of health and medical science. Medicinus accepts original ...