Indonesian Journal of Rheumatology
Vol. 14 No. 2 (2022): IJR VOL 14 No 2

Quantitative Evaluation of Proteinuria with Urinalysis Test and Comparing ItsCorrelation with Random Spot Urine PCR and 24-Hour Urine Protein in SLEPatients

Ruh Ng , Chun (Unknown)



Article Info

Publish Date
12 Dec 2022

Abstract

Introduction: Lupus nephritis is an important concern among systemiclupus erythematosus (SLE) patients in Asia, and its mortality rate wasreported to be 6 times higher compared to the general population. 24-hoururine protein collection has long been used as the gold standard test toassess proteinuria. This study aimed to assess the correlation of urinalysistest with random spot urine protein-creatinine ratio (PCR) compared with24- hour urine protein. Methods: This was a retrospective study. Theelectronic medical records of all SLE patients seen in the rheumatology clinic of Hospital Sultan Ismail from 1st January 2017 to 1st January 2021 were reviewed. Patients who had urinalysis, urine protein-creatinine ratio, and24-hour urine protein tests were identified. Data on demography, urinalysis, random spot urine protein-creatinine ratio, and 24-hour urine protein were obtained and analysed. Results: The correlation between urinalysis and 24hour urine protein was strong (r=0.702), whereas the correlation betweenurinalysis and urine PCR was stronger (r=0.797). Our study also showed thecorrelation between random urine protein-creatinine ratio and 24-hour urineprotein is strong (r=0.782). Conclusion: Urinalysis correlates well with bothrandom spot urine protein-creatinine ratio and 24-hour urine protein, andthe correlation is stronger with urine protein-creatinine ratio.  

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Journal Info

Abbrev

ijr

Publisher

Subject

Medicine & Pharmacology

Description

Indonesian Journal of Rheumatology is a peer-reviewed open access journal on rheumatic diseases and connective tissue disorders. This is an official journal of Indonesian Rheumatology Associantion (IRA) and published twice a year since 2009. Our mission is to encourage the development of scientific ...