<![CDATA[Background: Compliance with Standard Operating Procedures (SOPs) for the use of PPE remains low due to the lack of a safety culture in the workplace. Safety culture is influenced by behavioral, environmental, and personal factors. This study aims to analyze compliance with the use of Personal Protective Equipment (PPE) among Emergency Department (ER) personnel at Prabumulih City Hospital in 2025. Methods: This study used a cross-sectional design, with a population of 72 respondents and a sample size of 72. The sampling method used was total population sampling. This study was conducted from June 1 to July 1, 2025. Data collection and collection used a questionnaire. Results: Statistical analysis using Chi-Square and logistic regression showed a significant relationship (p-value <0.05) for the variables knowledge (p-value 0.036), attitude (p-value 0.000), length of service (p-value 0.019), training (p-value 0.025), supervision (p-value 0.014), waste management (p-value 0.017), availability of PPE (p-value 0.001), and no relationship with gender (p-value 0.719). Multivariate statistical analysis revealed that the dominant factor influencing PPE compliance was PPE availability (p=0.003; OR=14.213). Conclusion: It is recommended that education programs, supervision programs, and adequate PPE availability be improved to support officer compliance. Keywords: PPE, Availability, Compliance, Officers]]>
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