Jurnal Kedokteran Diponegoro
Vol 14, No 5 (2025): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)

DIFFERENTIATING APPENDICITIS TYPES: THE ROLE OF NEUTROPHIL SUBTYPES

Helman Kurniadi (Universitas Adiwangsa Jambi)
Timbul Partogi Haposan Simorangkir (1. Gatot Soebroto Army Central Hospital, Indonesia 2. Faculty of Military Pharmacy, The Republic of Indonesia Defense University)



Article Info

Publish Date
01 Sep 2025

Abstract

Background: Recent studies have highlighted the significance of inflammatory markers in diagnosing appendicitis; however, the specific roles of stab and segmented neutrophils in assessing disease severity remain poorly understood. Objective: This study aims to analyze the relationship between the types of appendicitis (complicated and uncomplicated) and neutrophil counts (stab and segmented), along with demographic variables such as age and gender, to evaluate their diagnostic significance. Methods: A retrospective, descriptive study was conducted on 48 appendicitis patients treated at Gatot Soebroto Army Central Hospital during 2020–2021. Data were analyzed using the Mann-Whitney U test, with a significance threshold set at p<0.05. Results: Neutrophil segment counts demonstrated a statistically significant difference between complicated and uncomplicated appendicitis cases (p=0.000), with higher levels observed in complicated cases. In contrast, neutrophil stab counts, age, and gender did not show statistically significant differences (p>0.05). Conclusion: Neutrophil segment counts serve as a reliable marker for assessing appendicitis severity, while neutrophil stab counts and demographic factors such as age and gender lack predictive value. Further research is warranted to investigate the temporal dynamics of neutrophil levels and their integration with other inflammatory markers.

Copyrights © 2025






Journal Info

Abbrev

medico

Publisher

Subject

Medicine & Pharmacology

Description

JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . ...