MEDICINUS
Vol. 39 No. 2: MEDICINUS

Relationship Between Serum Vitamin D Levels  and Anxiety Severity in Elderly Patients at the Internal Medicinie and Psychiatry Clinic of RSUP Prof. dr. I.G.N.G Ngoerah Denpasar

Helen Widiani (Unknown)
Tuty Kuswardhani (Unknown)



Article Info

Publish Date
01 Feb 2026

Abstract

Serum vitamin D plays an important role in both physical and mental health. Decreased serum vitamin D levels in the elderly are often associated with anxiety. This study aims to determine the relationship between serum vitamin D levelsand anxiety severity in elderly patients. A cross-sectional analytical study was conducted and subjects were recruited using consecutive sampling at RSUP Prof. dr. I.G.N.G. Ngoerah. Serum vitamin D levels were measured using the human vitamin D Chemiluminescent Microparticle Immunoassay (CMIA), and anxiety severity were assessed using the Geriatric Anxiety Inventory (GAI). The median age of the participants was 66.5 years (range: 60–83 years). The most common anxiety severity observed was mild (40%) and the most prevalent vitamin D status was insufficient (40%). Statisticalanalysis showed no significant correlation between serum vitamin D levels and anxiety severity (p=0.816). The Spearman correlation test yielded a p-value of 0.214 with a correlation coefficient of -0.125. However, path analysis revealed thatvitamin D indirectly affects anxiety severity through inflammatory bowel syndrome (IBS), with an effect size of -0.06 (p=0.035).

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Journal Info

Abbrev

journal

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Description

Tujuan penerbitan jurnal Medicinus adalah untuk meningkatkan wawasan dan menambah khasanah pengetahuan para praktisi medis dan farmasis di bidang kedokteran dan kefarmasian. Ruang lingkup dari jurnal ilmiah ini adalah publikasi artikel-artikel ilmiah yang bisa disajikan dalam bentuk penelitian ...