Parkinson's disease (PD) is a degenerative neurological disease, and at present there are no reliable laboratory tests for it. So how does this happen when people go to identify PD? vocal biomarkers, combined with machine learning (ML), seem to be an option for noninvasive diagnostics. In our work, we used a voice recording dataset which consisted of 26 different feature sets mined by various techniques. When using the extreme gradient boosting (XGBoost) method, out of all these models tested, an accuracy of 91.79% was achieved. As can be seen from its high precision, recall and F1- score, XGBoost performed very well in differentiating PD cases from non-cases. The study concludes that the application of ML, particularly XGBoost, to the diagnostic process can establish a valuable tool for early screening of PD, which will facilitate more speedy and correspondingly cost-effective clinical evaluations. This paper represents an important contribution to the rapidly developing fields of artificial intelligence-based on diagnosis of neurological diseases and digital health.
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