This study aims to analyze the effect of Debt to Equity Ratio (DER) on Return on Assets (ROA) at PT Kimia Farma Tbk. A quantitative method was applied by performing a simple linear regression analysis based on annual financial data. The regression results show that DER has a negative and significant impact on ROA, with a regression coefficient of –0.0152 and a significance value of 0.040, which is below the 0.05 threshold. The R Square value of 13.7% indicates that DER explains 13.7% of the variation in ROA. This study concludes that an increase in DER tends to reduce ROA, implying the importance of maintaining an optimal capital structure to support profitability.
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