THE IMPACT OF GREEN TEA ON BLOOD FLUIDITY IMPROVEMENT AND WEIGHT LOSS

Djoko Agus Purwanto (Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Airlangga University, Campus B, Jl. Dharmawangsa Dalam, Surabaya 60286, Indonesia)
Asri Darmawati (Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Airlangga University, Campus B, Jl. Dharmawangsa Dalam, Surabaya 60286, Indonesia)
purwaningsih purwaningsih (Department of Fundamental Nursing, Faculty of Nursing, Airlangga University, Surabaya, Indonesia)

Jurnal NERS
Vol. 9 No. 1 (2014): April 2014

Introduction: Various studies have shown the benefi cial effects of green tea, not only on cardiovascular diseases but also on type 2 diabetes.Methods: In this study, the preparation of green tea water extract has been standardized to (-)-epigalocatechin gallate (EGCG), the major component of green tea. The role of green tea water extract on blood fl uidity and diabetes diseases has been studied in 13 Fructose-Fed Rat (FFR). The rats were given high fructose diet ad libitum for one week and then combination with green tea water extract every day for 6 days.Results: The results show, green tea water extract can reduces 100 μL blood passage times of wistar rat signifi cantly (p<0.01) by Micro-Channel Array Flow Analyzer (MC-FAN) instrument. Green tea water extract also had strong effect in reducing abdominal fat (p<0.05), blood glucose level (p<0.01) and body weight (p<0.01).Conclusion: These results suggest that green tea water extract may has benefi cial effects for the treatment of diabetes and reduce blood viscosity.